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These agents mimic the incretin hormones, which enhance insulin secretion and suppress glucagon release, leading to potent effects on weight reduction and glycemic control

doi: 10.1038/s41586-020-2080-8 111 QingY.WangM.LinY

Theyre generally well-tolerated, but using too high a concentration or mixing with low-pH actives can cause mild irritation

Patients should also be prepared for the possibility of receiving instructions on self-care measures, such as sitz baths or over-the-counter remedies, which can help manage discomfort and promote healing

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